In this paper, a modified Buongiorno model is proposed and utilized to examine the nanoparticles distribution pattern in a nanofluid flow through a microchannel filled with a porous medium. The governing nonlinear differential equations are obtained and tackled numerically by using shooting method coupled with Runge-Kutta-Fehlberg integration scheme. Graphical results showing the effects of the pertinent parameters on the nanofluid velocity, nanoparticles concentration, skin friction and Sherwood number are presented and discussed quantitatively. It is found that nanoparticles tend to aggregate with high concentration along the microchannel centreline region, thus, lessens the skin friction and boosts the Sherwood number.