Starting from a humanistic perspective and based on the concept of sustainable development, this study analyzes the psychological needs and behavioral responses of consumers towards the packaging of cultural and creative products from the entry point of user groups. It explores the sustainable usage design methods for the packaging of cultural and creative products, thereby improving the recycling rate of the packaging and achieving the goal of reducing resource waste and protecting the environment. By employing Maslow’s Hierarchy of Needs, the study summarizes the acceptance needs of consumers for the packaging of cultural and creative products. The “Stimulus-Organism-Response” (SOR) theory is introduced to propose a model for the sustainable usage of packaging that integrates the display aspect throughout the entire life cycle of the product packaging (sales—use—recycling). A case study of the design improvement of packaging for cultural and creative cosmetics is used to practice the method. The appearance and convenience of the packaging affect the user’s perceptual structure, leading to a satisfactory psychology and sustainable usage behavior. The packaging design scheme for cultural and creative products, guided by these principles, not only meets the needs of businesses and consumers but also extends the usage cycle of the product packaging, realizing the sustainable use of resources.