With the increasing dynamics of the environment, the organisational innovation of high-end equipment manufacturing (HEM) enterprises has attracted more attention. This paper introduces a radial basis function (RBF) neural network to establish a model of the effect of organisational innovation on organisational performance (OP). Organisational innovation includes five dimensions: strategic innovation, structural innovation, cultural innovation, institutional innovation and process innovation. Through the modelling results, we know that all dimensions of organisational innovation have an effect on performance. According to the degree of impact, they are strategic innovation, structural innovation, process innovation, cultural innovation and institutional innovation.