The city administrative law-enforcing personnel (shorted to ‘chengguan’ in China) burnout is serious. How to timely detect, accurately measure and alleviate the burnout is an important issue for the new urban development areas in China. To construct the job demands-resources (JD-R) model, surveys in new urban areas of China were carried out. Results showed that burnout of chengguan was significantly different in terms of demographic characteristics. Job burnout of chengguan can be predicted by job demands and job resources. These findings can provide implications and guidance for the government sectors to reduce the intangible loss of human resources and to improve their health.