Due to the excellent broadcasting characteristics of radio signals, simultaneous wireless information and power transfer (SWIPT) can transmit both information and energy, and provide users with stable power supply. Wireless channel has the characteristics of openness, which will lead to the leakage of information in the SWIPT system. It is one of the research hotspots in the industry to ensure the secure transmission of information in SWIPT system where there are differences in the transmission of energy and information. This paper proposes an ‘information-energy’ dynamic switching opportunistic secure transmission scheme. First, a model considering three factors of multi-cell, multi-user and multiple eavesdropper is established which assumes that the user adopts a time-domain switching receiver that collects energy in a nonlinear model. Then, combined with the time-varying wireless channel, a dynamic information energy switching transmission scheme based on signal-to-interference noise ratio threshold is proposed. Finally, the energy and information transmission performance of the scheme are comprehensively analysed.