The close combination of modern science and modern art design has led design to the path of modernization with the aesthetic characteristics of “modernity”. The modern art design lacks in-depth research on its shape, aesthetic characteristics and color from the perspective of modern design, and rarely even conducts integration research from design innovation and application. Moreover, it has even less of a specific, systematic program of information integration. To this end, this paper analyzes the application of modern fine arts artistic modeling and color in modern art design. A neural network-based information fusion technology is proposed to realize the application of modern fine arts artistic modeling and color in modern art design. The information fusion technology maximizes the retention of the basic form and color combination of modern artistic model, and integrates color elements that are more in line with modern aesthetics to create a unique visual product of modern culture. The experimental results show that information fusion technology can effectively assist MAD.