This paper aims to investigate the influence path of Marx’s thought on contemporary college students’ thinking education, establishes a regression analysis model, determines the direction of the regression curve, uses the general analysis model to calculate the data of Marx’s thought as well as college students’ thinking education, and explores the influence of Marx’s thought on college students’ attitude towards Marx’s thought by analyzing the data of the influence situation of Marx’s thought on educated people and the data of college students’ attitude towards Marx’s thought. The data showed that 30.59% of the students were educated. The data results show that 30.59% of college students think that they can better show the national culture, 8.59% of college students feel that their after-school life is enriched, and 17.39% of college students feel happy. Only 12.9% of the educators only use textbooks for teaching, 10.77% of the educators use images in the classroom of university Civic Education, and 9.74% of the educators use short videos in the classroom of university Civic Education as a supplement so as to achieve the state of “no sound is better than sound at this time “This paper is a study of the influence of Marx’s thought on university education. This paper provides effective reference data for studying the influence path of Marx’s thought on university Civic Education.