When science and technology have been developed faster, many interior art design concepts and computer technology have been updated with the times. In this paper, the geometric data and semantic data in interior design are transformed through BIM modeling, the spatial structure elements are placed in the world coordinate system, and the relative coordinates are calculated with the spatial structure elements of the interior art design building entity as the origin. With the help of BIM technology, the interior art design layout is carried out. Based on the layout constraint function and spatial syntax quantization function, which constitute the layout objective optimization function, the optimization solution is calculated. Finally, Depthmap software is used to analyze the interior design layout for VGA and intelligent body simulation. The results show that after 100 iterations, the mean value of the coefficient of the degree of BIM application is 0.9373, the coefficient of the application environment is 0.951, and the degree of the application of the BIM technology shows a growing trend, indicating that the BIM technology is an inevitable direction for the reform of the interior art design technology.