At present, Chinese colleges and universities pursue “innovative talents” more strongly than ever. The status quo of creativity is closely related to the relatively low success rate of Chinese college students’ entrepreneurship. This paper combs the research results on the impact of creativity on college students’ entrepreneurial intention, and conducts a confirmatory analysis on the regulatory effect of creativity on entrepreneurial intention of Chinese vocational college students. This paper takes creativity as the independent variable, takes entrepreneurial intention as the dependent variable, makes an empirical analysis on the final sample data of 508 vocational college students, taking Chinese vocational college students as the survey objects. We find that creativity has a positive and distinctive impact on entrepreneurial intention of Chinese vocational college students. At the same time, we can see that there are obvious differences between entrepreneurial cultures of different countries and creativity of college students. It is suggested that the Chinese government should guide college students to cultivate entrepreneurial thinking, bring innovative thinking and adventurous spirit into their study and life, and actively advocate the establishment of a diversified and sustainable entrepreneurial ecology.