By constructing an endogenous growth model, this paper reveals the inner path of its development based on the rural cultural and creative economy. Secondly, by rationally allocating social resources and combining physical capital and cultural and creative capital, the inter-period optimization of consumption utility can be realized to the greatest extent. Finally, the endogenous economic growth model analyzes the economic effects of GDP and the H-village cultural creative tourism model in Guizhou Province. The results show that the correlation coefficient of the endogenous growth model of rural cultural creativity and economic development is R=0.979. The goodness of fit is R2 = 0.967, and the adjusted goodness of fit is R2 = 0.983, which indicates that the degree of proximity of the fitted equations to reality is extremely high. This paper provides the theoretical basis and practical guidance for developing a rural cultural and creative economy, which is of great significance for promoting the sustainable development of the regional economy.