Opera is an important part of Western music culture. Chinese Peking Opera and Western opera are a kind of art style focusing on expressiveness. Both of them are isomorphic to a certain extent, and they are different due to cultural differences. This paper takes Tan Dun’s opera “Marco Polo,” a hybrid work of art containing elements of Chinese Peking Opera and Western Opera, as the object of study and quantitatively analyzes the artistic characteristics and expressive forms of the work by means of arithmetic coding technology of audio signals and terminology acquisition and labeling model. According to the results, there are 15 labeled Beijing Opera singing tune fields in the work and 12 labeled locations, which indicate the destinations of Marco Polo’s travel process. The feasibility of the arithmetic coding quantization method, which was employed in the study of Tan Dun’s opera Marco Polo, is confirmed by the results.