This study ventures into the captivating realm of visual illusion art, where the enigmatic principles of visual perception are harnessed to enhance artistic creativity. Through mathematical modeling of the visual perception process, we uncover the essence of visual illusions and their profound impact on art and design. Leveraging cellular neural networks, this research merges dynamic processes with the WC visual illusion and color space models to craft a novel visual illusion neural network model adept at reproducing the nuances of visual illusion art. Our investigation into the application of visual illusions in art design reveals a notable affinity for the “transparent” quality, achieving a 57% certainty level and embodying the art’s ethereal nature. Furthermore, we identify significant correlations between interactive effects, color coordination, design structure, visual impact, and the overarching quality of art designs, with correlation indices of 0.508, 0.487, 0.535, and 0.602, respectively. This work highlights visual illusion’s pivotal role in propelling the field of art and design forward, thereby enriching the tapestry of human experience.