Applied Mathematics and Nonlinear Sciences
Journal license

Journal

Applied Mathematics and Nonlinear Sciences


Volume
& Issue

Volume 9, Issue 1


Published
on

January 31, 2024


Pages


DOI

Article

Application and research on the method of analyzing the composition of traditional Chinese medicine based on knowledge mapping

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Authors

Lin Wang Affiliation:
Department of Pharmaceutical Sciences and Health Management, Hebei Chemical and Pharmaceutical College, Shijiazhuang, Hebei, 050026, China.


Abstract

Modern experimental analysis techniques have the problem of inefficiency in the analysis of traditional Chinese medicine composition. For the construction of a knowledge graph of traditional Chinese medicine ingredients, this paper first proposes a two-way graph convolutional aggregation network model, which is characterized by the node features of the knowledge graph being enhanced by the relationship features in the initial embedding of entities and relationships. The performer model can reduce the computation of the attention score and improve the computational efficiency of the model. Next, the two-way graph convolutional aggregation network model is used to perform the analysis in the TCM-related database. Finally, the results of the analysis are applied to a real case study of traditional Chinese medicine composition analysis. The construction of the knowledge graph for traditional Chinese medicine ingredients resulted in the acquisition of 14 high-frequency keywords. In the results of the compositional analysis of the herbs of C. minor, 13 batches of samples could be clustered into three groups, and 11 common peaks and 4 common components were identified for the 13 batches of samples, which were protocatechuic acid, vanillic acid, caffeic acid, and chrysanthemic acid, respectively. A cumulative variance contribution of 84.853% was obtained after extracting three principal components.


Keywords

Graph convolutional network, Knowledge graph, Herbal components, Cluster analysis, Principal component analysis, 01A25


Citation

Wang, L. (2024). Application and research on the method of analyzing the composition of traditional chinese medicine based on knowledge mapping. Applied Mathematics and Nonlinear Sciences, 9(1). https://doi.org/10.2478/amns-2024-0234

Published by: Engineering Journals

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