This paper provides a detailed description of the key technologies of the ICC color management system, including device color matching, adaptive color gamut matching, and the color beauty optimization algorithm. A series of engineering experiments of color matching and cyclic optimization were carried out, and the case study method was used to obtain evaluation indexes such as color difference, color gamut, visual effect, and PBI index value and explore the advantages of ICC color management system application. The results demonstrate a significant reduction in the color difference value of the color block before and after the intelligent matching output, typically by 2–6 times. The maximum color difference in primary and secondary matching is no more than 4, and the color matching degree increases, indicating that intelligent matching is effective. In the interior decoration design case study, the PBI index increased from less than 50% to more than 50% after the optimization of the ICC color management system, while the mean value of the overall evaluation was higher, and the subjects were more agreeable to the design color evaluation.