Exploring effective ways to improve aesthetic education in colleges and universities is one of the hotspots of current educational research. Starting from the three dimensions of school theory, practical activities and social practice, this study successfully constructed a model of living and regionalizing aesthetic education in Hubei colleges and universities, integrating the elements of Jingchu culture using informatization tools. The study puts forward a series of hypotheses around the four key dimensions of school, society, policy and students. It uses factor analysis to explore the influencing factors behind these hypotheses and their interactions, ensuring the rationality of the influencing factors. This paper’s hypotheses are empirically supported by structural equation modeling verification. The model has been proved to be theoretically sound and practically feasible. The study results reveal that the mean values of all the influencing factors exceeded the median value of 3, and the standard deviations ranged from 0.7 to 1.0, showing a small degree of dispersion, which proved the reasonableness of the factor selection. Specifically, school support directly influences the living regionalization of aesthetic education in colleges and universities (0.628), while the indirect influence effects of social promotion, policy guarantee, and students’ attitudes are 0.240, 0.122, and 0.285, respectively. In addition, the combination of the Jingchu culture with aesthetic education in colleges and universities not only enhances the cultural self-confidence of college students, but also effectively carries forward the traditional culture, and provides a new perspective and practical path.