As an important cultural institution for urban cultural inheritance and construction, the complementarity, interaction, and development between university culture and urban culture are also getting more and more attention. This study analyzes the dynamic mechanism of the integration of university culture and urban culture by combining the dynamics model. Then, it constructs a dynamics model for the integration of urban culture into university culture based on the group dynamics theory and the airplane dynamics model. Then, a data-driven decision-making optimization scheme is proposed based on the BASM model, and a data-driven decision-making model oriented to the development of cultural integration is constructed with the data related to the artistic integration of universities as the driving basis. Finally, an empirical analysis of the integration development of culture between University M culture and Guangzhou city culture is carried out in Guangzhou city as an example, with a comprehensive average score of 92.70 for cultural recognition, and the correlation coefficients of the dimensions are highly correlated between 0.812 and 0.891. Meanwhile, the regression coefficients corresponding to the seven dimensions of cultural integration and development are all less than 0.05, and the VIF values are all less than 10. Moreover, the comprehensive average score of each dimension after optimization is 4.193, which is 0.79 points higher compared with that before optimization, and the satisfaction level is 1.297 points higher. In this paper, the optimization of the development strategy for the integration of university culture and urban culture can promote cultural integration and provide a specific optimization path for the integration of university culture and urban culture.