From the perspective of integrating social resources, the pre-incubator provides specialized training for college talents through in-depth cooperation between enterprises or governments and colleges and universities and guides the high-quality development of the vocational education system. This paper puts forward the basic model of information diffusion, based on the construction of an incubator network, combined with the role of incubator network nodes, and puts forward the information diffusion model of a “pre-incubator” network based on information content. The network structure of “pre-incubator” knowledge diffusion is analyzed with respect to the interest-matching degree of information content. Combined with the intrinsic connection between “pre-incubator” and a high-quality education system, we analyze the functional positioning of “pre-incubator” in higher vocational education. Combined with the descriptive statistics, analyze the role of “pre-incubator” on university-enterprise cooperation and innovation quality. The statistics show that the mean value of the number of patents of higher vocational institutions is 2.954, and the number of joint invention patents of university-enterprise is 0.721, and the estimation results show that, compared with the universities without higher vocational “pre-incubator”, the quality of innovation of the universities relying on the higher vocational “pre-incubator” is significantly improved after the establishment of the higher vocational “pre-incubator”. The results show that the quality of innovation of the universities based on the higher vocational “pre-incubator” is significantly improved after the establishment of the higher vocational “pre-incubator” compared with that of the universities without it.