In this essay, we examine the effect of computer science and artificial intelligence on international relations and political matters. Moreover, we mainly seek to understand the meaning of computer science and artificial intelligence and their effect on international relations and political matters. The essay at hand is analytical and expository, utilizes library research method to examine the subject of the essay. The results of this research state that the use of artificial intelligence initially is about symbolic aspects of science and innovative approaches of reasoning that means using ordinary hypotheses and simple rules. Researchers in the field of artificial intelligence normally have an empirical approach with a few mathematical theories. As in other sciences that the researchers create tools to carry out their empirical research, here the researchers create computer programs for the same purpose. There are new computer programs that have been created to present explanations on various theories about how intelligent function can be acquired. Moreover, the results of this essay state that artificial intelligence affects different dimensions of international relations and international policies and caused a serious transformation in this field. The most evident effect of artificial intelligence is in the hard-power area and the manufacture of artificial-intelligence-based weapons, so that soon humans are excluded from the decision-making cycle in attacks that are executed by these systems and AI-operated weapons can autonomously decide whether to perform an attack on a particular target or not. When this becomes real, it would be robots and droids that set foot in the battlefields and armed conflicts instead of human soldiers. Of course, AI can also be used in soft political fields, like anticipating social riots, foreign policy diplomacy, and the likes of that.