This study centers on the relationship between college management informatization, career planning and employability of art students. Using the college management informatization level scale, career planning scale, and employability scale as research tools, a survey was conducted with students of an art college as research subjects, and statistical methods such as multiple linear regression model, Pearson’s correlation coefficient, and mediation effect model were used to explore the relationship among college management informatization, career planning, and employability of art students. The overall level of college management education among art college students is higher than the theoretical median, and the significant difference is shown in grade level, not gender. The overall level of career planning among art college students is good, but there are significant differences in different dimensions related to demographic variables such as grade level. The theoretical median is lower than the overall level of employability, but there are significant differences in grade level. Collegiate information management positively predicts career planning and employability of art college students, and both career planning and employability positively predict each other. Art students’ career planning plays a mediating role between informationization of college management and employability.