This article uses BIM technology to simulate HVAC in a commercial building. And use fractional differential equations to verify the set temperature, humidity, and other related parameters. The experiment takes an air-conditioned room model as the research object and uses the thermodynamic characteristics to establish a dynamic mathematical model of differential equations. Research shows that the multiple electric heat pump equipment aggregation groups discussed in this article are a good resource for user-side demand response. The air-side flow rate disturbance of the building HVAC has the greatest impact on the heat transfer of the surface cooler. As the air velocity increases, the rate of increase in heat exchange will decrease.