Under the background of teaching in the new era, image recognition, operation, and processing of experimental data are still the focus of calculus teaching. Mathematica has powerful functions as mathematical software and was developed by Wolfram Research. Aiming at the complex symbols and data operation problems in many fields, the software flexibly combines mathematics branches such as geometry and algebra, dramatically simplifying the operation process. This paper takes Mathematica’s existing mathematical software as a reference to discuss whether the addition of such software helps improve the effectiveness of daily teaching. The study found that using this software can stimulate students’ interest and enhance the quality of education.