Higher education in India has grown rapidly since independence, becoming the world’s largest higher education country after the United States. In the research, the basic theory of higher education resource allocation efficiency was described. Then the regional distribution of higher education resources, the current situation of inputs and outputs in the central region were described. Then DEA analysis was used to evaluate the efficiency of higher education resources in the central region and projection analysis, and Tobit model was used to test the factors influencing the efficiency of higher education allocation in the central region. The efficiency evaluation and projection analysis of higher education resources in central region were conducted by using DEA analysis, and the Tobit model was used to test the factors influencing the efficiency of higher education allocation in central region. The empirical results show that the resource allocation efficiency of higher education in central region is not determined by education funding alone, but depends on the optimization of resource input combination.