In this paper, we first studied the demand for Chinese language communication, explored the mode of Chinese language communication, the process of Chinese language communication and the mode of interaction, and constructed a multivariate and three-dimensional communication path of Chinese language and culture. Then, a multiple linear regression model was established, the generalization error of the model was calculated, and the least squares method was used to find the optimal solution of the model parameters. Finally, the effect of cross-cultural communication in Chinese international education was evaluated, and the level of Chinese cultural awareness, Chinese cultural identity and Chinese cultural communication of the research participants were analyzed. The results show that the overall cultural awareness dimension of the survey respondents scored a total of 186 points, with an average score of 138.65 points, which is a medium level, indicating that Chinese intercultural communication and dissemination are more effective. This study promotes the development of international education and the in-depth development of international communication and cooperation.